NSHD – Age 68-70 – ACE-III Memory

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The MRC National Survey of Health of Development (NSHD) assessed their cohort members (CMs) during the study’s age 68-70 sweep using the Addenbrooke’s Cognitive Examination-III (ACE-III): Memory measure.

Details on this measure and the data collected from the CMs are outlined in the table below.

Domain:Verbal memory
CHC:Gc (Crystallised Intelligence)
Glr (long-term storage and retrieval)
Administration method:Research nurse. Mostly conducted using ACEmobile app, installed on iPad, with prompts to guide interviewer through the process. Pen and paper used where necessary (e.g. drawing tests).
Procedure:After the attention section was completed, participants were asked to recall the three words they were asked to remember ('lemon', 'key' and 'ball'; 0 - 3). Participants were then asked to memorise an address consisting of 7 elements. They were given two practice trials, and a third trial took place later in the interview; this was the only trial that was scored (0 - 7). Those who remembered all 7 elements of the address were given an additional 5 points. Those who got at least one element of the address wrong were then given primers to help them recall the correct elements (0 - 5). They were then asked to name: (i) the current Prime Minister; (ii) the first woman who was Prime Minister; (iii) the USA president; (iv) the USA president who was assassinated in the 1960 (0 - 4).
Link to questionnaire:https://skylark.ucl.ac.uk/NSHD/lib/exe/fetch.php?media=mrepo:ace-iii.pdf (opens in new tab)
Scoring:One point per correct answer (0 - 26)
Item-level variable(s):Not currently available
Total score/derived variable(s):ACESCRMM15x
Raw score
N = 1,787
Range = 7 - 26
Mean = 23.46
SD = 2.86
(click image to enlarge)
Age of participants (months):Mean = 834.14, SD = 2.93, Range = 828 - 848
Other sweep and/or cohort:None
Source:Mathuranath, P. S., Nestor, P. J., Berrios, G. E., Rakowicz, W., & Hodges, J. R. (2000). A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia. Neurology, 55(11), 1613-1620.
Technical resources:Noone, P. (2015). Addenbrooke's cognitive examination-III. Occupational Medicine, 65(5), 418-420.
Reference examples:Matías-Guiu, J. A., Valles-Salgado, M., Rognoni, T., Hamre-Gil, F., Moreno-Ramos, T., & Matías-Guiu, J. (2017). Comparative diagnostic accuracy of the ACE-III, MIS, MMSE, MoCA, and RUDAS for screening of Alzheimer Disease. Dementia and Geriatric Cognitive Disorders, 43(5-6), 237-246.
James, S. N., Davis, D., O'Hare, C., Sharma, N., John, A., Gaysina, D., ... & Richards, M. (2018). Lifetime affective problems and later-life cognitive state: Over 50 years of follow-up in a British birth cohort study. Journal of Affective Disorders, 241, 348-355.

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This page is part of CLOSER’s ‘A guide to the cognitive measures in five British birth cohort studies’.